Tóm tắt

The improvement of enzymatic glucose sensors, which have outstanding advantages such as high sensitivity,rngood selectivity, and convenient operation, is crucial because of the increasing demand for the diabeticsrndetection. Here, we prepared the ZnONRs-based glucose sensor by hydrothermally synthesizing the ZnO nanornrods (ZnONRs) on a flexible PET substrate. The electrodeposited reduced graphenes (rGO) with differentrndeposition cycles were coated onto the ZnONRs to modify the surface of working electrodes. The high conrnductivity of rGO promoted the transmission of redox electrons, which significantly improved electron transportrnbetween solution and electrode. Also, the rGO smoothed the rough surface of the working electrodes, whichrnnegligibly increased the contact angles, reduced the contacting surface area between the working electrodes andrnthe PBS solution, and further decreased the enzyme adsorption that influences the redox electron yield.rnNevertheless, the former positive effect was more significant than the latter negative one, which eventually gavernrise to better performance of the rGO/ZnONR-based glucose sensors. Thereby, in the Nafion/GOx/rGO-20/rnZnONRs/Au/PET sensors, the sensitivity increased by 9.2 times, the detection limit decreased by 47 times,rnand the linear range was extended from 7.5 mM to 12 mM, compared with sensors without rGOs. Additionally,rnboth of the ZnONRs-based and rGO/ZnONRs-based glucose sensors show strong anti-interference performance inrnthe test environment containing urea, uric acid, and ascorbic acid