Tóm tắt

Powders of cerium (Ce)-substituted and tungsten (W)-substituted La2Mo2O9(LMO) were prepared using poly-merizable complex method. Their antiviral and antibacterial performances were then evaluated using bacter-iophage Qβ, bacteriophage Φ6,Escherichia coli, and Staphylococcus aureus. The obtained powders, which werernalmost single-phase, exhibited both antiviral and antibacterial properties. Effects of dissolved ions on theirrnantiviral activity against bacteriophage Qβwere remarkable. A certain contribution of direct contact to thernpowder surface was also inferred along with the dissolved ion effect for antiviral activity against bacteriophagernΦ6. Dissolved ion effects and pH values suggest that both Mo and W are in the form of polyacids. Antiviralrnactivity against bacteriophageΦ6 was improved by substituting Ce for La in LMO. Similarly to LMO, Ce-sub-stituted LMO exhibited hydrophobicity. Inactivation of alkaline phosphatase enzyme proteins was inferred asrnone mechanism of the antiviral and antibacterial activities of the obtained powders.